The Los Angeles County Department of Public Health (LAC DPH) issued a health update on September 9, 2022. This advisory shares important information about monkeypox patients with severe disease, testing, and vaccines.
- Patients with severe monkeypox disease and those at risk of severe disease should be treated with tecovirimat.
- Intravenous tecovirimat should be used in patients who are unable to take oral therapy, who may have impaired oral drug absorption, or who are failing to improve on oral therapy.
- Severe outcomes have been observed in people with inadequately treated HIV; both CD4 count and viral load should be considered when assessing risk.
- Clinicians must report hospitalizations due to monkeypox to LAC DPH. In addition, they are asked to call the LAC DPH consultation line if a hospitalized patient is worsening clinically, such as being admitted to the ICU. LAC DPH will provide clinical consultation and access to additional therapeutic options.